Endometriosis Pain Relief with Cannabis
Endometriosis is known to be a painful and complicated disease; however, cannabis is helpful for endometriosis pain relief.
Many women experience the debilitating and common condition of endometriosis.
A tissue called endometrium lines the uterus, and overgrowth of this tissue causes endometriosis. There are many side effects of this disease which include nausea, constipation, gastrointestinal upsets especially diarrhea, painful intercourse, dysmenorrhea (painful menstrual periods), and chronic pelvic pain.
In some severe cases, endometriosis results in infertility.
Endometriosis is very difficult to diagnose and treat because the cause of this disease is still unknown. A big problem associated with the endometriosis pain relief is that the treatment for one woman may not work for another.
Right now, there is no cure for endometriosis; however, marijuana can be used for endometriosis pain relief.
ESC (Endocannabinoid System)
Human body contains a group of cannabinoid receptors which is called Endocannabinoid System or ECS. Most components of ECS are present in endometrial tissue. Scientists have studied the rodent models of endometriosis. It revealed that menstrual cycle regulates the ECS levels in the body.
These ECS levels include:
- FAAH (fatty acid amide hydrolase). It is an enzyme which breaks down endocannabinoids.
- NAPE-PLD (N-acyl phosphatidylethanolamine phospholipase D). It is an enzyme which synthesizes endocannabinoids.
- CB1 and CB2 (Type 1 and Type 2 cannabinoid receptors).
AEA (endocannabinoid anandamide) is a chemical which is produced by the body, and it is similar in structure to THC. The highest concentration of this chemical in the reproductive system is found in the uterus.
Connection of Cannabinoid to Endometriosis
The deficiency of ECD (endocannabinoid) is connected to endometriosis. It is observed that women with lower levels of CB1 receptor in their endometrial tissues have endometriosis. The growth of endometriosis is due to reduced ECS function. The growth occurs throughout the body along with increased pain. It is the CB1 receptor which brings endometriosis pain relief.
The endometriosis cells in human divide and grow less when they are stimulated with WIN 55212-2. It is a synthetic cannabinoid used for the proliferation of endometriosis cells. Scientists conducted various studies of endometriosis on rodents. They found that rodents had more pain when they were treated with AM251. It is a drug which inhibits the cannabinoid receptors. The scientists also found that rodents had less pain when they were treated with WIN 55212-2.
Medical Marijuana for Endometriosis Pain Relief
Cannabis plant contains the cannabinoids called phytocannabinoids.
There is extensive scientific evidence which shows that phytocannabinoids are very helpful for endometriosis pain relief, and almost all symptoms of the endometriosis.
In addition to this, these cannabinoids also provide relief to muscle cramping, inflammation, fatigue, anxiety, headaches, depression and many more problems.
Smoking increases the risk of blood clots in women who are on hormonal treatments for endometriosis.
Therefore, women with endometriosis should strictly avoid smoking if using hormonal treatments.
You can purchase different variations of cannabis in Canada, including:
- Dried Flowers
- Edibles
- CBD Oils
- Concentrates, such as Budder and Shatter
Women with endometriosis have two options:
They can either use cannabis oils or vaporize marijuana flowers. Vaporizing it will combust the cannabis which will release many types of cannabinoids. Each of them have unique health benefits.